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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Biological Reference Interval for Hematological Profile of Umbilical Cord Blood: A Study Conducted at A Tertiary Care Centre in South India
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Biological Reference Interval for Hematological Profile of Umbilical Cord Blood: A Study Conducted at A Tertiary Care Centre in South India

机译:脐血血液学特征的生物学参考区间:在印度南部三级护理中心进行的一项研究

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Introduction: Umbilical cord blood (UCB) a source of hematopoietic stem cells, is also an acceptable sample to assess neonatal sepsis. Though reports are available for stem cell counts very minimal literature is available regarding hematologic parameters, which may vary on ethnicity. Aim: To establish biological reference interval for hematological parameters of umbilical cord blood to guide neonatologists, hematopoietic stem cell transplant specialists and future analysis. Materials and Methods: Prospective longitudinal study was done from January 2014 to April 2014 after ethics committee approval. UCB from 120 full term new borns of normal birth weight born out of uneventful pregnancy to mothers aged between 21 to 45 years with hemoglobin above 10g/dL were processed in Beckman Coulter LH780 analyzer for complete blood count and counter checked by peripheral smear. Results tabulated in Microsoft excel are analyzed using IBM SPSS statistics 16 software. Results: Male to female ratio is 1:1.05. There is no difference in the values between males and females. When compared with few studies available, though many values are comparable a few values are not comparable. Conclusion: This study can be a useful guide to neonatologists, hematopoietic stem cells transplant hematologists and future analysis.
机译:简介:脐血(UCB)是造血干细胞的来源,也是评估新生儿败血症的可接受样本。尽管有关于干细胞计数的报告,但有关血液学参数的文献很少,这可能因种族而异。目的:建立脐带血血液学参数的生物学参考区间,以指导新生儿科医生,造血干细胞移植专家及今后的分析。材料和方法:前瞻性纵向研究在伦理委员会批准后于2014年1月至2014年4月进行。在Beckman Coulter LH780分析仪中对从120例正常出生的足月正常出生体重正常婴儿出生至21至45岁且血红蛋白高于10g / dL的母亲进行UCB进行全血细胞计数并通过外周涂片检查进行检查。使用IBM SPSS statistics 16软件分析Microsoft excel中列表的结果。结果:男女之比为1:1.05。男性和女性之间的值没有差异。当与少数可用研究进行比较时,尽管许多值是可比较的,但有些值是不可比较的。结论:该研究可为新生儿科医生,造血干细胞移植血液学家和未来分析提供有益的指导。

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