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A Study Of Body Mass Index In Healthy Individuals And Its Relationship With Fasting Blood Sugar

机译:健康人体重指数及其与空腹血糖的关系研究

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Background and objectives: Obesity is a global epidemic and is on the rise. It is defined as a body mass index (BMI) which is equal to or more than 30. It is one of the modifiable risk factors of type 2 diabetes. This study was undertaken to assess the association between BMI and fasting blood sugar (FBS) and also to verify whether BMI increases with age. Subjects and Methods: This prospective study included 400 healthy adult individuals who met the inclusion criteria. Fasting blood samples were collected to measure FBS by the glucose oxidase method. Thirty individuals were excluded from the study, as their blood glucose levels were in the diabetic range. Results: Among 370 individuals, a positive correlation was observed (Pearson?s correlation coefficient r = + 0.26) between BMI and FBS. There was a stepwise increase in the magnitude of BMI with an increase in age in decades. Although the increase in mean FBS was observed with age, a statistically significant (p = 0.00093) increase in mean FBS was observed only in the 4th decade of life. Interpretation and conclusions: The observed positive correlation between BMI and FBS reiterates the diabetogenic effect of adipose tissue and emphasizes the importance of the maintenance of normal BMI to prevent the early onset of diabetes.
机译:背景和目标:肥胖是一种全球流行病,并且正在上升。它被定义为等于或大于30的体重指数(BMI)。它是2型糖尿病的可修正危险因素之一。这项研究旨在评估BMI与空腹血糖(FBS)之间的关联,并验证BMI是否随年龄增加。受试者和方法:这项前瞻性研究纳入了符合纳入标准的400名健康成人。采集空腹血样以通过葡萄糖氧化酶法测量FBS。由于他们的血糖水平在糖尿病范围内,因此有30名患者被排除在研究之外。结果:在370名个体中,BMI和FBS之间存在正相关(Pearson相关系数r = + 0.26)。随着年龄的增长,BMI的数量逐步增加。尽管观察到平均FBS随着年龄的增长而增加,但仅在生命的第40个十年中观察到统计学上显着的(P = 0.00093)显着增加。解释和结论:观察到的BMI与FBS之间的正相关性重申了脂肪组织的致糖尿病作用,并强调了维持正常BMI对预防糖尿病早期发作的重要性。

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