How Vps41 HOPS between tethering functions

摘要

![Figure][1]/imgIn the absence of Yck3 (right), Vps41 relocalizes from vacuoles to endosomes.Cabrera et al. reveal how phosphorylation alters the membrane-tethering activity of Vps41, allowing the protein to operate in two distinct trafficking pathways.Vps41 is part of the HOPS complex that