首页> 外文期刊>Journal of Clinical Microbiology >Rapid Molecular Detection of Inducible Macrolide Resistance in Mycobacterium chelonae and M. abscessus Strains: a Replacement for 14-Day Susceptibility Testing?
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Rapid Molecular Detection of Inducible Macrolide Resistance in Mycobacterium chelonae and M. abscessus Strains: a Replacement for 14-Day Susceptibility Testing?

机译:快速的分子检测在分支杆菌和脓毒杆菌中可诱导的大环内酯类药物耐药性:替代14天药敏试验?

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摘要

The erm(41) gene causes inducible macrolide resistance in Mycobacterium abscessus but not Mycobacterium chelonae. erm(41) sequencing of 285 M. abscessus and 45 M. chelonae isolates was compared to 14-day susceptibility; agreement percentages were 98.9% and 100%, respectively. Extended incubation may not be necessary for M. chelonae, and the erm(41) genotype is a useful adjunct for M. abscessus.
机译: erm (41)基因在脓肿分枝杆菌中引起可诱导的大环内酯类抗药性,而在螯合分枝杆菌中则没有。比较了285 M.脓肿和45 M chelonae分离株的 erm (41)测序与14天敏感性的比较。协议百分比分别为98.9%和100%。 chelonae不一定需要长时间孵育,而 erm (41)基因型是脓肿分枝杆菌的有用辅助物。

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