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Distribution of Phage-Associated Virulence Genes in Pharyngeal Group A Streptococcal Strains Isolated in Italy

机译:噬菌体相关毒力基因在意大利分离的咽喉A群链球菌菌株中的分布

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The presence and assortment of 16 known virulence/resistance genetic determinants carried by prophages or prophage-like elements were tested in 212 clinical group A Streptococcus (GAS) strains and related to available data from SmaI macrorestriction/pulsed-field gel electrophoresis analysis and emm typing. A strong correlation existed among the three analyses. This finding supports the substantial contribution to the evolution and diversification of the GAS genome attributed to phages.
机译:在212例临床A组链球菌(GAS)菌株中测试了由前噬菌体或类似前噬菌体元素携带的16种已知毒力/抗性遗传决定因素的存在和分类,并与SmaI宏观限制性/脉冲刺激的可用数据相关场凝胶电泳分析和 emm 分型。这三个分析之间存在很强的相关性。该发现支持归因于噬菌体的GAS基因组对进化和多样化的实质性贡献。

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