Wnt7b Regulates Placental Development in Mice

Brian A Parr; Valerie A Cornish; Myron I Cybulsky; Andrew P McMahon

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Wnt7b Regulates Placental Development in Mice

机译：Wnt7b调节小鼠胎盘发育

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SecretedWntproteinsregulatemanydevelopmentalprocessesinmulticellularorganisms.WehavegeneratedatargetedmutationinthemouseemWnt/em7bgene.HomozygousemWnt/em7bmutantmicedieatmidgestationstagesasaresultofplacentalabnormalities.emWnt/em7bexpressioninthechorionisrequiredforfusionofthechorionandallantoisduringplacentaldevelopment.Theα4integrinprotein,requiredforchorioallantoicfusion,isnotexpressedbycellsinthemutantchorion.Wnt7balsoisrequiredfornormalorganizationofcellsinthechorionicplate.Thus,Wnt7bsignalingiscentraltotheearlystagesofplacentaldevelopmentinmammals./p/div

机译：SecretedWntproteinsregulatemanydevelopmentalprocessesinmulticellularorganisms.Wehavegeneratedatargetedmutationinthemouse <位置>的Wnt 的7bgene.Homozygous <位置>的Wnt 的7bmutantmicedieatmidgestationstagesasaresultofplacentalabnormalities。<在>的Wnt 的7bexpressioninthechorionisrequiredforfusionofthechorionandallantoisduringplacentaldevelopment.Theα4integrinprotein，requiredforchorioallantoicfusion，isnotexpressedbycellsinthemutantchorion.Wnt7balsoisrequiredfornormalorganizationofcellsinthechorionicplate.Thus，Wnt7bsignalingiscentraltotheearlystagesofplacentaldevelopmentinmammals。

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《Developmental biology》 |2001年第2期|共页
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Brian A Parr; Valerie A Cornish; Myron I Cybulsky; Andrew P McMahon;
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1. Wnt7b regulates placental development in mice [J] . Parr BA, Cornish VA, Cybulsky MI, Developmental biology . 2001,第2期

机译：Wnt7b调节小鼠胎盘发育
2. Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/beta-catenin signaling pathway [J] . Zhang Cong, Yang Xiuqin, Fu Chen, Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2018,第期

机译：与TMZ和MIR-505的组合通过调节WNT7B / WNT /β-Catenin信号传导途径来抑制胶质母细胞瘤的发育
3. Wnt7b Signaling from the Ureteric Bud Epithelium Regulates Medullary Capillary Development [J] . Roker LaToya Ann, Nemri Katrina, Yu Jing Journal of the American Society of Nephrology: JASN . 2017,第1期

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4. Formation and sustained-dissociation of antitumor platinum-loaded micelles regulated by secondary structure of poly(amino acids) in their core [C] . Yuki Mochida, Albertini Francesco, Horacio Cabral, World biomaterials congress . 2012

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5. Campylobacter rectus infection impairs placental function and development in mice. [D] . Bobetsis, Georgios A. 2006

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6. Circ_0105346 Knockdown Inhibits Osteosarcoma Development via Regulating miR-1182/WNT7B Axis Retraction [O] . 2021

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7. Wnt7b Regulates Placental Development in Mice [O] . Parr Brian A, Cornish Valerie A, Cybulsky Myron I, 2001

机译：Wnt7b调节小鼠胎盘发育

Wnt7b Regulates Placental Development in Mice

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