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Dynamic expression of a cell surface protein during rearrangement of epithelial cells in the Manduca wing monolayer☆

机译:Manduca翼单层上皮细胞重排过程中细胞表面蛋白的动态表达☆

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Theexpressionofcellsurfaceprotein2F5changesdynamicallyinspaceandtimeduringmorphogenesisoftheManducawingpattern.Twocelltypes(generalizedepithelialcellsandscaleprecursors)rearrangewithineachofthetwoepithelialmonolayersofthewingtoformperiodicrowsofscalecells.Thesetwomonolayersalsointeractwitheachotherduringabriefperiodofadultdevelopment.Eachcelltypeshowsadifferentpatternofprotein2F5expressionduringcellrearrangementandduringinteractionofthetwowingmonolayers.Beforeandafterthesemorphogeneticmovementsofepithelialcells,theproteinisexpressedononlyasmallpopulationofwingcells.Inabdominalepitheliawherescalecellsarealsopresentbutarenotarrangedinperiodicrows,theexpressionpatternofthesurfaceproteinistemporallyandspatiallyverydifferent.Anearlierstudy(NardiandMagee-Adams,Dev.Biol.,116,278a€“290,1986)hadshownthatbasalprocessesonlyextendfromepithelialcellsduringtheirperiodofrearrangementwithinamonolayerandduringthetransientappositionofthewing'supperandlowermonolayers.Thedifferentialdistributionofprotein2F5onlateralsurfacesandbasalprocessesofscaleprecursorcellsandgeneralizedepithelialcellsmayaccountinpartfortheirorderlysegregationintoalternatingrowsaswellasforthetransientinteractionofthetwowingmonolayers.
机译:Theexpressionofcellsurfaceprotein2F5changesdynamicallyinspaceandtimeduringmorphogenesisoftheManducawingpattern.Twocelltypes(generalizedepithelialcellsandscaleprecursors)rearrangewithineachofthetwoepithelialmonolayersofthewingtoformperiodicrowsofscalecells.Thesetwomonolayersalsointeractwitheachotherduringabriefperiodofadultdevelopment.Eachcelltypeshowsadifferentpatternofprotein2F5expressionduringcellrearrangementandduringinteractionofthetwowingmonolayers.Beforeandafterthesemorphogeneticmovementsofepithelialcells,theproteinisexpressedononlyasmallpopulationofwingcells.Inabdominalepitheliawherescalecellsarealsopresentbutarenotarrangedinperiodicrows,theexpressionpatternofthesurfaceproteinistemporallyandspatiallyverydifferent.Anearlierstudy(NardiandMagee亚当斯,Dev.Biol,116,278a€“290,1986。)hadshownthatbasalprocessesonlyextendfromepithelialcellsduringtheirperiodofrearrangementwithinamonolayerandduringthetransientappositionofthewing' supperandlowermonolayers.Thedifferentialdistributionofpro在前表面细胞和广义上皮细胞的横向表面和基本过程中,tein2F5可能是部分原因导致了它们在交替行中的交替分离以及两个机翼单层的瞬态相互作用。

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