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Implications of the Eighth Joint National Committee Guidelines for the Management of High Blood Pressure for Aging AdultsNovelty and Significance

机译:第八届全国联合委员会《老年人高血压管理指南》的意义新颖性和意义

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The recent 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults from the Eight Joint National Committee Panel may significantly affect the aging US population. We performed a cross-sectional analysis of black and white participants in Atherosclerosis Risk in Communities who participated in the fifth study visit (2011–2013). Sitting blood pressure was calculated from the average of 3 successive readings taken after a 5-minute rest. Currently, prescribed antihypertensive medications were recorded by reviewing medication containers brought to the visit. Blood pressure control was defined using both the Seventh and Eighth Joint National Committee thresholds. Of 6088 participants (mean age, 75.6 [range, 66–90] years, 58.4% women; 23.2% black), 54.9% had either diabetes mellitus or chronic kidney disease. The prevalence of hypertension according to Seventh Joint National Committee thresholds was 81.9%, and 62.8% of the entire sample were at blood pressure goal. Using the Eighth Joint National Committee thresholds, 79.4% were at blood pressure goal (16.6% were reclassified as at-goal). Reclassification was higher for individuals with diabetes mellitus or chronic kidney disease (20.6%) when compared with individuals without either condition (11.6%). The use of antihypertensive medications in our cohort was high, with 75.0% prescribed at least 1 antihypertensive medication and 46.7% on ≥2 antihypertensive agents. In conclusion, in a US cohort of aging white and black individuals, ≈1 in 6 individuals were reclassified as having blood pressure at goal by Eighth Joint National Committee guidelines. Despite these less aggressive goals, >20% remain uncontrolled by the new criteria.# Novelty and Significance {#article-title-25}
机译:八联合全国委员会最近发布的2014年循证指南的成人高血压管理指南可能会严重影响美国老龄人口。我们对参加第五次研究访问(2011-2013年)的社区中动脉粥样硬化风险的黑人和白人参与者进行了横断面分析。静坐血压由休息5分钟后的3次连续读数的平均值计算得出。目前,处方药是通过复查来访的药物容器来记录的。使用第七和第八联合全国委员会的阈值定义了血压控制。在6088名参与者中(平均年龄75.6 [范围[66-90]岁],女性58.4%;黑人23.2%),54.9%患有糖尿病或慢性肾脏病。根据第七联合全国委员会的阈值,高血压的患病率为81.9%,整个样本的62.8%为血压目标。使用第八届全国联合委员会阈值,达到血压目标的比例为79.4%(重新分类为正常目标的比例为16.6%)。患有糖尿病或慢性肾脏疾病的个体的重分类较高(20.6%),而没有任何一种情况的个体(11.6%)则更高。在我们的队列中,抗高血压药物的使用率很高,其中75.0%的患者至少使用一种抗高血压药物,而46.7%的患者使用≥2种抗高血压药物。总而言之,在美国一个年龄较大的白人和黑人个体中,根据第八联合全国委员会的指南,每6个人中约有1个人被归类为血压达到目标。尽管目标不那么激进,但仍有超过20%的新标准无法控制。#新颖性和意义{#article-title-25}

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