N2-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis

摘要

A new method was developed to synthesize N ~(2) -alkyl-substituted 1,2,3-triazoles via gold catalyzed alkylation of vinyl ethers with mono- and unsubstituted NH-1,2,3-triazoles and benzotriazole. A hydrogen bond between the oxygen atom of the vinyl ethers, activated via the gold catalyst, and the NH-1,2,3-triazoles was supposed to be generated, which selectively gave the N ~(2) -alkylation products.