Role of Vascular Endothelial Growth Factor (VEGF) and B-Cell Lymphoma / Leukemia-2 (Bcl-2) in the Pathogenesis of LupusNephritis and Their Correlation to Clinicopathological Indices of Disease Activity.

Ahmed Saeed Abdel Haleem Saad; Manal I Salman; Elham I Seif

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Role of Vascular Endothelial Growth Factor (VEGF) and B-Cell Lymphoma / Leukemia-2 (Bcl-2) in the Pathogenesis of LupusNephritis and Their Correlation to Clinicopathological Indices of Disease Activity.

机译：血管内皮生长因子（VEGF）和B细胞淋巴瘤/白血病2（Bcl-2）在狼疮性肾炎发病中的作用及其与疾病活动的临床病理指标的关系。

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ABSTRACT Serum concentrations of vascular endothelial growth factor(VEGF) and B cell lymphoma leukemia-2(Bcl-2) may be relevant in the pathogenesis and activity of lupus nephritis. Plasma concentrations of VEGF were found to be increased in patients with active lupus nephritis as a result of the presence of tissue hypoxia, inflammation and endothelial damage with disease activity. It was also over expressed in renal tissue from these patients. Serum levels of Bcl-2 were found to be elevated in .

机译：摘要血清血管内皮生长因子（VEGF）和B细胞淋巴瘤白血病2（Bcl-2）的浓度可能与狼疮性肾炎的发病和活动有关。发现活动性狼疮性肾炎患者的血浆VEGF浓度升高，这是由于组织缺氧，炎症和对疾病活动性的内皮损害所致。在这些患者的肾组织中也过表达。发现血清Bcl-2水平升高。

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《Research Journal of Pharmaceutical, Biological and Chemical Sciences》 |2015年第1期|共页
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Ahmed Saeed Abdel Haleem Saad; Manal I Salman; Elham I Seif;
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1. Role of Vascular Endothelial Growth Factor (VEGF) and B-Cell Lymphoma / Leukemia-2 (Bcl-2) in the Pathogenesis of LupusNephritis and Their Correlation to Clinicopathological Indices of Disease Activity. [J] . A. BENSLAMA, M. MOUMNI, S. ZAIM Research Journal of Pharmaceutical, Biological and Chemical Sciences . 2015,第1期

机译：血管内皮生长因子（VEGF）和B细胞淋巴瘤/白血病2（Bcl-2）在狼疮性肾炎发病中的作用及其与疾病活动的临床病理指标的关系。
2. Role of gelatinases (MMP-2 and MMP-9), TIMP-1, vascular endothelial growth factor (VEGF), and microvessel density on the clinicopathological behavior of childhood non-Hodgkin lymphoma. [J] . Citak EC, Oguz A, Karadeniz C, Pediatric Hematology and Oncology . 2008,第1a4期

机译：明胶酶（MMP-2和MMP-9），TIMP-1，血管内皮生长因子（VEGF）和微血管密度在儿童非霍奇金淋巴瘤临床病理行为中的作用。
3. Does vascular endothelial growth factor (VEGF) play a role in the pathogenesis of minimal change disease? [J] . Boner G, Cox AJ, Kelly DJ, Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association . 2003,第11期

机译：血管内皮生长因子（VEGF）在微小变化疾病的发病机理中是否起作用？
4. Role of Vascular Endothelial Growth Factor-D (VEGF-D) on IL-6 Expression in Cerulein-Stimulated Pancreatic Acinar Cells [C] . JANGWON LEE, KYUNG HWAN KIM, HYEYOUNG KIM Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：血管内皮生长因子-D（VEGF-D）对小分子刺激的胰腺腺泡细胞IL-6表达的作用
5. Vascular endothelial growth factor (VEGF), BCL-2, and Bax expression in fibropapilloma tumor tissue and skin tissue of sea turtles. [D] . Bancalari-Schmidlapp, Angela. 2009

机译：血管内皮细胞生长因子（VEGF），BCL-2和Bax在海龟的纤维乳头状瘤肿瘤组织和皮肤组织中的表达。
6. Vascular Endothelial Growth Factor (VEGF)-Mediated Angiogenesis Is Associated with Enhanced Endothelial Cell Survival and Induction of Bcl-2 Expression [O] . Jacques E. Nör, Joan Christensen, David J. Mooney, 1999

机译：血管内皮生长因子（VEGF）介导的血管生成与增强的内皮细胞存活和Bcl-2表达的诱导有关。
7. Does vascular endothelial growth factor (VEGF) play a role in the pathogenesis of minimal change disease? [O] . G. Boner 2003

机译：血管内皮生长因子（VEGF）是否在最小变化疾病的发病机制中发挥作用？

Role of Vascular Endothelial Growth Factor (VEGF) and B-Cell Lymphoma / Leukemia-2 (Bcl-2) in the Pathogenesis of LupusNephritis and Their Correlation to Clinicopathological Indices of Disease Activity.

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