ABSTRACT Pulsatile drug delivery systems (PDDS) are gaining importance nowadays that delivers the drug at specific time as per the pathophysiological need of the disease resulting in improved patient therapeutic efficacy and compliance. In this PDDS, floating pulsatile concept is specifically applied to increase the gastric resistance of the dosage form having lag phase in stomach followed by a burst release in the distal small intestine which minimize the inter and intra-subject variability du.
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