ABSTRACT Investigations of herbal medicines may provide a novel drug for the treatment of pain, without addiction liability and gastric discomfort caused by opioids and nonsteroidal anti-inflammatory agents respectively. In the current study, an aqueous extract of Polygonum glabrum (PG) was evaluated for its putative analgesic activity in rodents. Hence the effects of the PG extract were evaluated through validated animal models of pain including acetic acid-induced writhing test, tail flick la.
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