Variable reproducibility in genome‐scale public data: A case study using ENCODE ChIP sequencing resource

首页> 外文期刊>FEBS Letters >Variable reproducibility in genome‐scale public data: A case study using ENCODE ChIP sequencing resource

【24h】

Variable reproducibility in genome‐scale public data: A case study using ENCODE ChIP sequencing resource

机译：基因组规模公共数据中的可变重现性：使用ENCODE ChIP测序资源的案例研究

获取原文

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Genome‐widedataisaccumulatinginanunprecedentedwayinthepublicdomain.Re‐miningthisdatashowsgreatpotentialtogeneratenovelhypotheses.Howeverthisapproachisdependentonthequality(technicalandbiological)oftheunderlyingdata.Hereweperformedasystematicanalysisofchromatinimmunoprecipitation(ChIP)sequencingdataoftranscriptionandepigeneticfactorsfromtheencyclopaediaofDNAelements(ENCODE)resourcetodemonstratethataboutonethirdofconditionswithreplicatesshowlowconcordancebetweenreplicatepeaklists.Thisservesasacasestudytodemonstrateacaveatconcerninggenome‐wideanalysesandhighlightsaneedtovalidatethequalityofeachsamplebeforeperformingfurtherassociativeanalyses...

机译：基因组widedataisaccumulatinginanunprecedentedwayinthepublicdomain.Re-miningthisdatashowsgreatpotentialtogeneratenovelhypotheses.Howeverthisapproachisdependentonthequality（technicalandbiological）oftheunderlyingdata.Hereweperformedasystematicanalysisofchromatinimmunoprecipitation（芯片）sequencingdataoftranscriptionandepigeneticfactorsfromtheencyclopaediaofDNAelements（ENCODE）resourcetodemonstratethataboutonethirdofconditionswithreplicatesshowlowconcordancebetweenreplicatepeaklists.Thisservesasacasestudytodemonstrateacaveatconcerninggenome-wideanalysesandhighlightsaneedtovalidatethequalityofeachsamplebeforeperformingfurtherassociativeanalyses ...

著录项

来源
《FEBS Letters》 |2015年第1期|共5页
作者

展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类分子生物学;
关键词

相似文献

外文文献
中文文献
专利

1. Variable reproducibility in genome-scale public data: A case study using ENCODE ChIP sequencing resource [J] . Devailly Guillaume, Mantsoki Anna, Michoel Tom, FEBS letters. . 2015,第24aPta2期

机译：基因组规模公共数据中的可变重现性：使用ENCODE ChIP测序资源的案例研究
2. Validation of survival-associated biomarkers in solid tumors using publicly available gene chip and next generation sequencing data [J] . Gyorffy Balazs, Pongor Lorinc, Nagy Adam, International journal of molecular medicine . 2015,第Suppla1期

机译：使用公开可用的基因芯片和下一代测序数据验证实体瘤中与生存相关的生物标记
3. It's complicated: criteria for policy decisions for the clinical integration of genome‐scale sequencing for reproductive decision making [J] . Benjamin S. Wilfond Molecular Genetics & Genomic Medicine . 2015,第4期

机译：这很复杂：用于生殖决策的基因组规模测序的临床整合的政策决策标准
4. Transcription Control in Human Cell Types by Systematic Analysis of ChIP Sequencing Data from the ENCODE [C] . Guillaume Devailly, Anagha Joshi International work-conference on bioinformatics and biomedical engineering . 2017

机译：通过系统分析来自ENCODE的ChIP测序数据来控制人类细胞中的转录
5. Scalable bus encoding for error-resilient high-speed on-chip communication. [D] . Karmarkar, Kedar. 2013

机译：可扩展的总线编码，可实现高容错性的高速片上通信。
6. Variable reproducibility in genome-scale public data: A case study using ENCODE ChIP sequencing resource [O] . Guillaume Devailly, Anna Mantsoki, Tom Michoel, -1

机译：基因组规模公共数据中的可变重现性：使用ENCODE ChIP测序资源的案例研究
7. Variable reproducibility in genome-scale public data: A case study using ENCODE ChIP sequencing resource [O] . Devailly Guillaume, Mantsoki Anna, Michoel Tom, 2015

机译：基因组规模公共数据中的可变重现性：使用ENCODE ChIP测序资源的案例研究
8. National Study of Resource-Based Relative Value Scales for Physician Services. Volume 5. Documentation for Resource-Based Relative Value Study Data Tape [R] . Hsiao, W. C. , Braun, P. , Becker, E. , 1988

机译：基于资源的医师服务相对价值量表的国家研究。第5卷。基于资源的相对价值研究数据磁带的文档

Variable reproducibility in genome‐scale public data: A case study using ENCODE ChIP sequencing resource

摘要

著录项

相似文献

相关主题

期刊订阅