Changes in activity and F1 content of mitochondrial H+‐ATPase in regenerating rat liver

摘要

>Submitochondrial particles prepared from rat liver during hepatic regeneration exhibit a depressed ATPase activity which is correlated with a decrease in F₁ subunit content as shown by SDS-PAGE. Use of an antibody directed against the F₁ portion of the H+-ATPase complex demonstrated that there is a definite decrease in the amount of β-subunit of F₁ in both Submitochondrial particles and mitochondria from rat liver 24 h after partial hepatectomy