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首页> 外文期刊>Nucleic acids research >GREENC: a Wiki-based database of plant lncRNAs
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GREENC: a Wiki-based database of plant lncRNAs

机译:GREENC:基于Wiki的植物lncRNAs数据库

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Long non-coding RNAs (lncRNAs) are functional non-translated molecules greater than 200 nt. Their roles are diverse and they are usually involved in transcriptional regulation. LncRNAs still remain largely uninvestigated in plants with few exceptions. Experimentally validated plant lncRNAs have been shown to regulate important agronomic traits such as phosphate starvation response, flowering time and interaction with symbiotic organisms, making them of great interest in plant biology and in breeding. There is still a lack of lncRNAs in most sequenced plant species, and in those where they have been annotated, different methods have been used, so making the lncRNAs less useful in comparisons within and between species. We developed a pipeline to annotate lncRNAs and applied it to 37 plant species and six algae, resulting in the annotation of more than 120 000 lncRNAs. To facilitate the study of lncRNAs for the plant research community, the information gathered is organised in the Green Non-Coding Database (GreeNC, http://greenc.sciencedesigners.com/).
机译:长非编码RNA(lncRNA)是大于200 nt的功能性非翻译分子。它们的作用是多种多样的,它们通常参与转录调控。除少数例外,LncRNA在植物中仍未进行大量研究。经实验验证的植物lncRNA可调节重要的农艺性状,例如磷酸盐饥饿反应,开花时间以及与共生生物的相互作用,这使它们在植物生物学和育种中引起了极大兴趣。在大多数已测序植物物种中仍然缺少lncRNA,并且在已注释植物的情况下,使用了不同的方法,因此使lncRNA在种内和种间比较中的用处不大。我们开发了注释lncRNA的管道,并将其应用于37种植物和6种藻类,从而注释了12万多个lncRNA。为了促进植物研究团体对lncRNA的研究,在绿色非编码数据库(GreeNC,http://greenc.sciencedesigners.com/)中组织了收集到的信息。

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