Comparative Antibiotic Resistance of Diarrheal Pathogens from Vietnam and Thailand, 1996-1999

摘要

Antimicrobial resistance rates for shigella, campylobacter, nontyphoidal salmonella, and enterotoxigenicEscherichia coli were compared for Vietnam and Thailand from 1996 to 1999. Resistance to trimethoprim-sulfamethoxazole, ampicillin, chloramphenicol, and tetracycline was common. Quinolone resistanceremains low in both countries, except among campylobacter and salmonella organisms in Thailand. Nalid-ixic acid resistance among salmonellae has more than doubled since 1995 (to 21%) in Thailand but is notyet documented in Vietnam. Resistance to quinolones correlated with resistance to azithromycin in bothcampylobacter and salmonella in Thailand. This report describes the first identification of this correlationand its epidemiologic importance among clinical isolates. These data illustrate the growing magnitude ofantibiotic resistance and important differences between countries in Southeast Asia