Human Infection with MERS Coronavirus after Exposure to Infected Camels, Saudi Arabia, 2013

摘要

Middle East respiratory syndrome coronavirus (MERS- ?????????????????????????????????????????????????????????????????????????????????????????????????????? from a patient who died of pneumonia in Saudi Arabia (1). ?????????????????????????????????????????????????????????????????????????????????????????????????????????????????? of MERS-CoV infection, most resulting in respiratory tract illness, have been reported to the World Health Organization; 97 of these cases were fatal. Known cases have been directly or indirectly linked to countries in the Arabian Peninsula (2). Dromedary camels across and beyond the region show high rates of antibodies against MERS-CoV (3–7), and viral RNA has been detected in camels in different countries (8,9). In 1 instance, a camel and 2 humans caring for the camel were found to be infected with viruses that were highly similar but distinct within 4,395 nt of the camel- derived virus sequence, including several phylogenetically informative nucleotide changes (10). To investigate possible camel–human virus transmission, we analyzed an infection with MERS-CoV in a man after he had contact with an infected camel.