Concomitant cryptococcal and tuberculous meningitis in a patient with systemic lupus erythematosus

摘要

Background: Infection is a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). Cryptococcal and tuberculous meningitis are opportunistic infections that can be fatal, especially among immunocompromised patients. Concomitant central nervous system infection with cryptococcosis and tuberculosis (TB) is unusual but has been reported in immunodeficiency states such as infection with human immunodeficiency virus (HIV). However, this is very rare in SLE patients, with just one published case in the literature.