A diagnostic approach to detect murine Shistosoma mansoni infection using a polymerase chain reaction

摘要

Background: Traditional diagnosis of Schistosoma mansoni infection involves direct microscopic detection of eggs in feces. The use of some stool concentration techniques may increase the diagnostic yield. However, it seems that the sensitivity of parasitological methods diminishes when prevalence and intensity of infection are low, making these methods less appropriate for low-endemic areas and in post treatment situations.