Analysis of Chikungunya Genome Sequences from Bagan Panchor, Malaysia

摘要

Background: Chikungunya virus (CHIKV) of East Central/South Africa (ECSA) genotype has recently caused outbreaks in the Indian Ocean from 2005 to 2007. In April 2006, there was an outbreak of CHIKV infection in Malaysia which involved an estimated 200 villagers in Bagan Panchor (BP), Perak. Partial sequencing of E1, E2, and nsP1 regions showed that the outbreak was due to a strain of the Asian genotype. Complete genome sequences of Malaysian isolates have not yet been reported, but would be useful for detailed study of differences between genotypes.