The relationship between macrolide resistance in Streptococcus pneumoniae and consumption of oral macrolides in Republic of Croatia and City of Zagreb

摘要

Background: The aim of this study was to investigate the relationship between increased resistance of Streptococcus pneumoniae to macrolides and use of macrolides in Croatia from 2001 to 2008, with the special emphasis on differences in outpatient consumption of macrolides in City of Zagreb and total consumption in Republic of Croatia.