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PREPARATION OF AN IMMUNOSUPPRESSIVE MACROLIDE POWDER FOR ORAL SUSPENSION
PREPARATION OF AN IMMUNOSUPPRESSIVE MACROLIDE POWDER FOR ORAL SUSPENSION
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机译:口服悬浮剂的免疫抑制性巨石粉的制备
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摘要
The present invention describes pharmaceutical compositions that comprise a tacrolimus powder for oral suspension that exhibits great stability as a powder for suspension and also, once prepared, as the extemporaneous suspension, without the formation of cake-like clusters, same having a satisfactory flavour and a pleasant aroma. The invention also describes the method for preparing the pharmaceutical compositions, same being a dry method that comprises mixing tacrolimus and pre-sieved pharmaceutically acceptable carriers for a suitable length of time, and the use of the pharmaceutical compositions for treating and preventing rejection of transplanted organs and atopic dermatitis.
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