HCV Treatment with Pegylated Interferon and Ribavirin in Patients with Haemophilia and HIV/HCV Coinfection: A Retrospective Review

摘要

Background: Adult patients with haemophilia are frequently coinfected with HIV and HCV, usually due to blood and plasma factor transfusion prior to effective screening programs. The current standard therapy for HCV is pegylated interferon and ribavirin (PEG?+?RBV), which has been investigated in HCV monoinfection and HIV/HCV coinfection. Little data exists regarding the effectiveness of HCV therapy in coinfected patients with haemophilia. We reviewed HCV treatment outcomes in our cohort of patients with haemophilia and HIV/HCV coinfection.