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A Booster Vaccination with Mycobacterium bovis BCG Does Not Increase the Protective Effect of the Vaccine against Experimental Mycobacterium ulcerans Infection in Mice

机译:牛分枝杆菌卡介苗的加强疫苗接种不会增加疫苗对小鼠实验性溃疡分枝杆菌感染的保护作用

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摘要

Buruli ulcer, caused by Mycobacterium ulcerans, is a necrotizing skin disease emerging particularly in West Africa. M. bovis BCG vaccine offers only short-term protection against experimental footpad infection of C57BL/6 mice with M. ulcerans, and the duration of this protection cannot be prolonged by a booster vaccination.
机译:由溃疡分枝杆菌引起的布鲁氏溃疡是一种坏死性皮肤病,特别是在西非。 M。 bovis BCG疫苗仅对C57BL / 6小鼠实验性脚垫感染 M提供短期保护。溃疡,并且加强免疫不能延长这种保护的持续时间。

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