CSTNPD: A Database for Cancer Specific Toxic Natural Products

摘要

Objective: To compile an open access central resource database for cancer specific toxic natural products. Methods: The literature survey using PubMed was made manually in order to collect the natural product that exhibit anticancer activity but not or least toxic to normal cell, and were curated by in an open access central resource database. Result: The compound database provides opportunities for researchers to obtain various information required for the successful identification of pharmaceutically relevant substances. Application: The bioactive natural products with anticancer therapeutic potential are abundantly reported, but majority of them are toxic to normal cells too. All those novel natural product molecules failed to proceed towards further detailed research or to reach into clinical trial and pharmaceutical drug development and drug approval.