Phase I|[sol]|II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

M T Huggett; M Jermyn; A Gillams; R Illing; S Mosse; M Novelli; E Kent; S G Bown; T Hasan; B W Pogue; S P Pereira

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Phase I|[sol]|II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

机译：Verteporfin光动力疗法在局部晚期胰腺癌中的I | [sol] | II期研究

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Background:Patients with pancreatic cancer have a poor prognosis apart from the few suitable for surgery. Photodynamic therapy (PDT) produces localised tissue necrosis but previous studies using the photosensitiser meso-tetrahydroxyphenylchlorin (mTHPC) caused prolonged skin photosensitivity. This study assessed a shorter acting photosensitiser, verteporfin.

机译：背景：胰腺癌患者除少数适合手术的患者外，预后较差。光动力疗法（PDT）会产生局部组织坏死，但先前使用光敏剂中四羟基苯氯（mTHPC）的研究导致皮肤光敏性延长。这项研究评估了一种较短作用的光敏剂韦替泊芬。

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《British Journal of Cancer 》 |2014年第7期| 共7页
作者
M T Huggett; M Jermyn; A Gillams; R Illing; S Mosse; M Novelli; E Kent; S G Bown; T Hasan; B W Pogue; S P Pereira;
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中图分类肿瘤学 ;
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1. Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer [J] . M T Huggett, M Jermyn, A Gillams, British Journal of Cancer . 2014 ,第7期

机译：Verteporfin光动力疗法在局部晚期胰腺癌中的I / II期研究
2. Chemoradiotherapy with concurrent gemcitabine and cisplatin with or without sequential chemotherapy with gemcitabine|[sol]|cisplatin vs chemoradiotherapy with concurrent 5-fluorouracil in patients with locally advanced pancreatic cancer |[ndash]| a multi-centre randomised phase II study [J] . R Wilkowski, S Boeck, S Ostermaier, British Journal of Cancer . 2009 ,第11期

机译：并发吉西他滨和顺铂联合或不联合吉西他滨| [sol] |顺铂的放化疗与放疗联合5-氟尿嘧啶的局部放化疗| [ndash] |多中心随机II期研究
3. Phase 1 study of EUS-guided photodynamic therapy for locally advanced pancreatic cancer [J] . DeWitt John M., Sandrasegaran Kumar, ONeil Bert, Gastrointestinal Endoscopy . 2019 ,第2期

机译：局部引导光动力治疗局部晚期胰腺癌的第1阶段研究
4. Photodynamic therapy of locally advanced pancreatic cancer (VERTPAC study): final clinical results [C] . Huggett MT, Jermyn M, Gillams A, Optical methods for tumor treatment and detection: mechanisms and techniques in photodynamic therapy XXII . 2013

机译：局部晚期胰腺癌的光动力疗法（VERTPAC研究）：最终临床结果
5. I. Cyclodextrin dimers and timers in peptide binding, protein inhibition, and photodynamic cancer therapy. II. Studies toward synthesis of a stable symmetrical cyclopropenyl anion [D] . Leung, David K. 2001

机译：I.环糊精二聚体和定时器，用于肽结合，蛋白质抑制和光动力癌症治疗。二。合成稳定的对称环丙烯基阴离子的研究
6. Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer [O] . M T Huggett, M Jermyn, A Gillams, 2014

机译：Verteporfin光动力疗法在局部晚期胰腺癌中的I / II期研究
7. Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer [O] . M T Huggett, M Jermyn, A Gillams, 2014

机译：临床胰腺癌中Verteporfin光动力治疗的I / II研究

Phase I|[sol]|II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

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