Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours

A O von Bueren; M D Bacolod; C Hagel; K Heinimann; A Fedier; U Kordes; T Pietsch; J Koster; M A Grotzer; H S Friedman; G Marra; M Kool; S Rutkowski

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Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours

机译：错配修复缺陷：髓母细胞瘤细胞系中的替莫唑胺抗性因子在原发性髓母细胞瘤肿瘤中不常见

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Background:Tumours are responsive to temozolomide (TMZ) if they are deficient in O6-methylguanine-DNA methyltransferase (MGMT), and mismatch repair (MMR) proficient.

机译：背景：如果肿瘤缺乏O6-甲基鸟嘌呤-DNA甲基转移酶（MGMT）和错配修复（MMR），则它们对替莫唑胺（TMZ）有反应。

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《British Journal of Cancer》 |2012年第8期|共10页
作者
A O von Bueren; M D Bacolod; C Hagel; K Heinimann; A Fedier; U Kordes; T Pietsch; J Koster; M A Grotzer; H S Friedman; G Marra; M Kool; S Rutkowski;
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中图分类肿瘤学;
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1. Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours [J] . A O von Bueren, M D Bacolod, C Hagel, British Journal of Cancer . 2012,第8期

机译：错配修复缺陷：髓母细胞瘤细胞系中的替莫唑胺抗性因子在原发性髓母细胞瘤肿瘤中不常见
2. PLK1 Inhibition Targets Myc-Activated Malignant Glioma Cells Irrespective of Mismatch Repair Deficiency-Mediated Acquired Resistance to Temozolomide [J] . Higuchi Fumi, Fink Alexandria L., Kiyokawa Juri, Molecular cancer therapeutics . 2018,第12期

机译：PLK1抑制靶向MYC活化的恶性胶质瘤细胞，无论不匹配修复缺乏介导的抗替代唑胺抗性
3. Proteomic profiling of isogenic primary and metastatic medulloblastoma cell lines reveals differential expression of key metastatic factors [J] . Gu Shuo, Chen Kai, Yin Minzhi, Journal of proteomics . 2017,第期

机译：等源性原发性和转移性Medulloblastoma细胞系的蛋白质组学分析显示了关键转移因子的差异表达
4. High-Frequency Dielectrophoresis Characterization of Differentiated vs Undifferentiated Medulloblastoma Cells [C] . Remi Manczak, Sofiane Saada, Mirella Tanori, EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields . 2018

机译：分化的高频介电泳表征与未分化的Medulloblastoma细胞的特征
5. Perifosine, a novel Akt inhibitor induces apoptosis, cell cycle arrest and has a chemo-sensitizing effect in medulloblastoma cell lines. [D] . Kumar, Anil. 2010

机译：Perifosine是一种新型Akt抑制剂，可诱导凋亡，阻止细胞周期并在髓母细胞瘤细胞系中具有化学增敏作用。
6. Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours [O] . A O von Bueren, M D Bacolod, C Hagel, 2012

机译：错配修复缺陷：髓母细胞瘤细胞系中的替莫唑胺抗性因子在原发性髓母细胞瘤肿瘤中不常见
7. Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours [O] . von Bueren, A O, Bacolod, M D, Hagel, C, 2012

机译：错配修复缺陷：髓母细胞瘤细胞系中的替莫唑胺抗性因子在原发性髓母细胞瘤肿瘤中不常见

Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours

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