Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer

J H Huh; T H Kim; K Kim; J-A Song; Y J Jung; J-Y Jeong; M J Lee; Y K Kim; D H Lee; H J An

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Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer

机译：miR-106a和miR-591的失调赋予紫杉醇对卵巢癌的抵抗力

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Background:MicroRNAs are noncoding regulatory RNAs strongly implicated in carcinogenesis, cell survival, and chemosensitivity. Here, microRNAs associated with chemoresistance in ovarian carcinoma, the most lethal of gynaecological malignancies, were identified and their functional effects in chemoresistant ovarian cancer cells were assessed.

机译：背景：MicroRNA是非编码调控RNA，与致癌作用，细胞存活和化学敏感性密切相关。在这里，鉴定了与妇科恶性肿瘤中最致命的卵巢癌化学耐药性相关的微小RNA，并评估了其在化学耐药性卵巢癌细胞中的功能作用。

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《British Journal of Cancer》 |2013年第2期|共10页
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J H Huh; T H Kim; K Kim; J-A Song; Y J Jung; J-Y Jeong; M J Lee; Y K Kim; D H Lee; H J An;
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中图分类肿瘤学;
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1. Microvesicles mediate transfer of P-glycoprotein to paclitaxel-sensitive A2780 human ovarian cancer cells, conferring paclitaxel-resistance [J] . Fang-fang Zhang, Yi-fei Zhu, Qian-nan Zhao, European Journal of Pharmacology: An International Journal . 2014,第Null期

机译：微泡介导P糖蛋白向紫杉醇敏感的A2780人卵巢癌细胞的转移，赋予紫杉醇耐药性
2. lncRNA-PRLB Confers Paclitaxel Resistance of Ovarian Cancer Cells by Regulating RSF1/NF-kappa B Signaling Pathway [J] . Zhao Yuzi, Hong Li Cancer biotherapy and radiopharmaceuticals . 2021,第2期

机译：LNCRNA-PRLB通过调节RSF1 / NF-Kappa B信号通路来赋予卵巢癌细胞的紫杉醇抗性
3. Mitochondria P-glycoprotein confers paclitaxel resistance on ovarian cancer cells [J] . Min Li, Weihong Dong, Weina Guo, OncoTargets and therapy . 2019,第2期

机译：线粒体P糖蛋白赋予紫杉醇对卵巢癌细胞的抗性
4. Akt Involvement in Paclitaxel Chemoresistance of Human Ovarian Cancer Cells [C] . SU-HYEONG KIM, YONG-SUNG JUHNN, YONG-SANG SONG Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：Akt参与人类卵巢癌细胞紫杉醇的耐药性
5. Peritumorally activatable nanoparticles for delivery of paclitaxel to multidrug resistant ovarian cancer cells. [D] . Gullotti, Emily S. 2012

机译：用于紫杉醇递送至多药耐药性卵巢癌细胞的可经皮激活的纳米颗粒。
6. Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer [O] . J H Huh, T H Kim, K Kim, 2013

机译：miR-106a和miR-591的失调赋予紫杉醇对卵巢癌的抵抗力
7. Clusterin Interacts with Paclitaxel and Confer Paclitaxel Resistance in Ovarian Cancer12 [O] . Park, Dong Choon, Yeo, Seung Geun, Wilson, Mark R, 2008

机译：Clusterin与紫杉醇相互作用并赋予卵巢癌紫杉醇抗药性12

Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer

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