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Physical and psychosocial outcomes in cancer patients: a comparison of different age groups

机译:癌症患者的身体和社会心理预后:不同年龄组的比较

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In a cross-sectional study, we investigated the relationship between age, physical health, social and economic resources, functional status, activities of daily living (ADL) and disease-related variables of 227 patients with cancer. Using multidimensional outcome measures we examined age differences in three age groups ( 65 years) and identified predictors of performing ADL. The results indicated that older patients have outcomes similar to those of younger patients. There were no significant differences in quality of life, performance status and physical health among the three age groups. The only areas where age-related differences were found were co-morbidity and cancer-related impairments. Patients aged 45-65 years and patients 65 years and older reported a higher level of co-morbidity and more cancer-related impairments than those aged 45 and younger. Although older patients had higher co-morbidity, they showed similar Karnofsky Performance Status (KPS) scores to those of their younger counterparts. The regression analysis revealed social resources, self-reported health, performance status and complexity of care as significant predictors of patients' ADL, but not age, co-morbidity or severity of treatment. The findings support the conclusion that differences in performing ADL between younger and older patients with cancer are minimal and tend to be due to co-morbidity. Thus, treatment should be decided by a patient's physical health rather than by age.
机译:在一项横断面研究中,我们调查了227例癌症患者的年龄,身体健康,社会和经济资源,功能状态,日常生活活动(ADL)与疾病相关变量之间的关系。使用多维结局指标,我们检查了三个年龄组(65岁)的年龄差异,并确定了进行ADL的预测因素。结果表明,老年患者的结局与年轻患者相似。三个年龄组的生活质量,表现状态和身体健康状况无显着差异。发现与年龄相关的差异的唯一区域是合并症和与癌症相关的损伤。与45岁及以下的患者相比,年龄在45-65岁之间的患者和65岁及以上的患者发生并发疾病的程度更高,并且与癌症相关的损伤更多。尽管老年患者的合并症较高,但他们的Karnofsky绩效状态(KPS)评分与年轻患者相似。回归分析显示,社交资源,自我报告的健康状况,表现状况和护理的复杂性是患者ADL的重要预测指标,但不是年龄,合并症或治疗严重程度的重要预测指标。这些发现支持这样的结论,即年轻和老年癌症患者在进行ADL方面的差异很小,并且往往是由于合并症。因此,治疗应根据患者的身体健康而不是年龄来决定。

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