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Licit prescription drug use in a Swedish population according to age, gender and socioeconomic status after adjusting for level of multi-morbidity

机译:调整多重发病率水平后,瑞典人根据年龄,性别和社会经济状况使用合法处方药

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Background There is a great variability in licit prescription drug use in the population and among patients. Factors other than purely medical ones have proven to be of importance for the prescribing of licit drugs. For example, individuals with a high age, female gender and low socioeconomic status are more likely to use licit prescription drugs. However, these results have not been adjusted for multi-morbidity level. In this study we investigate the odds of using licit prescription drugs among individuals in the population and the rate of licit prescription drug use among patients depending on gender, age and socioeconomic status after adjustment for multi-morbidity level. Methods The study was carried out on the total population aged 20?years or older in ?sterg?tland county with about 400 000 inhabitants in year 2006. The Johns Hopkins ACG Case-mix was used as a proxy for the individual level of multi-morbidity in the population to which we have related the odds ratio for individuals and incidence rate ratio (IRR) for patients of using licit prescription drugs, defined daily doses (DDDs) and total costs of licit prescription drugs after adjusting for age, gender and socioeconomic factors (educational and income level). Results After adjustment for multi-morbidity level male individuals had less than half the odds of using licit prescription drugs (OR 0.41 (95% CI 0.40-0.42)) compared to female individuals. Among the patients, males had higher total costs (IRR 1.14 (95% CI 1.13-1.15)). Individuals above 80?years had nine times the odds of using licit prescription drugs (OR 9.09 (95% CI 8.33-10.00)) despite adjustment for multi-morbidity. Patients in the highest education and income level had the lowest DDDs (IRR 0.78 (95% CI 0.76-0.80), IRR 0.73 (95% CI 0.71-0.74)) after adjustment for multi-morbidity level. Conclusions This paper shows that there is a great variability in licit prescription drug use associated with gender, age and socioeconomic status, which is not dependent on level of multi-morbidity.
机译:背景技术人群和患者之间合法处方药的使用存在很大差异。事实证明,除纯医学因素外,其他因素对于开具合法药物也很重要。例如,具有较高年龄,女性性别和低社会经济地位的人更可能使用合法处方药。但是,这些结果尚未针对多发病率水平进行调整。在这项研究中,我们根据人群的性别,年龄和社会经济状况,对人群中使用合法处方药的几率进行了调查,并对患者中合法处方药的使用率进行了调整。方法这项研究是对2006年斯特兰特县20岁以上的总人口(约40万居民)进行的。约翰·霍普金斯(Johns Hopkins)ACG病例组合被用来代表个人多层次人群的水平。在调整了年龄,性别和社会经济因素之后,我们已经将使用合法处方药的患者的个体比值比和发病率比(IRR),定义的日剂量(DDDs)和合法处方药的总成本相关联的人群中的发病率因素(教育程度和收入水平)。结果在调整了多发病水平后,男性患者使用合法处方药的几率不到女性(OR 0.41(95%CI 0.40-0.42))。在这些患者中,男性的总费用较高(IRR 1.14(95%CI 1.13-1.15))。尽管对多种疾病进行了调整,但80岁以上的人使用合法处方药的几率是九倍(OR 9.09(95%CI 8.33-10.00))。经过多发病率调整后,教育和收入水平最高的患者的DDD最低(IRR 0.78(95%CI 0.76-0.80),IRR 0.73(95%CI 0.71-0.74)。结论本文表明,合法处方药的使用与性别,年龄和社会经济状况有关,存在很大的差异,这与多种疾病的发病率无关。

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