Synthesis and NMR Studies of Core-Modified, N-Confused Porphyrins Possessing Alkyl Groups at the Rim Nitrogen

摘要

The `3+1`type condensation of 16-thiatripyrromethane with N-alkyl-2,4-bis[(メ+hydroxy-メ-phenyl)methyl]pvrole in the presence of acid catalyst afforded core-modified, N-confused porphyrins bearing alkyl groups at the rim nitrogen. The proton NMR spectra indicate that the bulkiness of the N-alkyl substituents is somewhat relatedwith the tiltedness of the inverted pyrrole ring. The changes in chemical shift of inner methine protons depending on the N-alkyl group and protonation site is discussed.