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Multimorbidity and comorbidity in the Dutch population?–?data from general practices

机译:荷兰人口中的多发病和合并症?

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Background Multimorbidity is increasingly recognized as a major public health challenge of modern societies. However, knowledge about the size of the population suffering from multimorbidity and the type of multimorbidity is scarce. The objective of this study was to present an overview of the prevalence of multimorbidity and comorbidity of chronic diseases in the Dutch population and to explore disease clustering and common comorbidities. Methods We used 7?years data (2002–2008) of a large Dutch representative network of general practices (212,902 patients). Multimorbidity was defined as having two or more out of 29 chronic diseases. The prevalence of multimorbidity was calculated for the total population and by sex and age group. For 10 prevalent diseases among patients of 55?years and older (N?=?52,014) logistic regressions analyses were used to study disease clustering and descriptive analyses to explore common comorbid diseases. Results Multimorbidity of chronic diseases was found among 13% of the Dutch population and in 37% of those older than 55?years. Among patients over 55?years with a specific chronic disease more than two-thirds also had one or more other chronic diseases. Most disease pairs occurred more frequently than would be expected if diseases had been independent. Comorbidity was not limited to specific combinations of diseases; about 70% of those with a disease had one or more extra chronic diseases recorded which were not included in the top five of most common diseases. Conclusion Multimorbidity is common at all ages though increasing with age, with over two-thirds of those with chronic diseases and aged 55?years and older being recorded with multimorbidity. Comorbidity encompassed many different combinations of chronic diseases. Given the ageing population, multimorbidity and its consequences should be taken into account in the organization of care in order to avoid fragmented care, in medical research and healthcare policy.
机译:背景技术越来越多的发病率被认为是现代社会面临的主要公共卫生挑战。但是,缺乏关于患有多发病的人口规模和多发病类型的知识。这项研究的目的是概述荷兰人群中慢性病的多种发病率和合并症的流行,并探讨疾病的聚集和常见合并症。方法我们使用了一个7年的数据(2002-2008年),该数据来自大型的荷兰代表性常规诊治网络(212,902名患者)。多发病定义为在29种慢性疾病中有两种或两种以上。根据总人口以及性别和年龄组计算出多发病率。对于55岁及以上(N≥52014)患者中的10种流行疾病,采用logistic回归分析研究疾病的聚类和描述性分析,以探讨常见的合并症。结果在13%的荷兰人口和55岁以上的37%的人口中发现了慢性病的多发病。在55岁以上患有特定慢性疾病的患者中,超过三分之二还患有一种或多种其他慢性疾病。大多数疾病对的发生频率要比疾病独立时的预期发生频率高。合并症不仅限于特定的疾病组合;约有70%的疾病患者记录了一种或多种额外的慢性疾病,这些疾病未列入最常见的前五种疾病中。结论尽管所有年龄段的多发病率均随年龄增长而增加,但超过三分之二的慢性病患者以及55岁及以上年龄段的多发病率均记录在案。合并症包括许多慢性疾病的不同组合。鉴于人口老龄化,在医疗研究和医疗保健政策中,在护理的组织中应考虑多种疾病及其后果,以避免分散的护理。

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