Background The prevalence of metabolic syndrome (MS) has been increasing in China in recent years. The aim of this study is to estimate and compare the prevalence of MS among Chinese adults in Shanghai, one of the most economic developed areas in China, using definitions proposed by World Health Organization (WHO), National Cholesterol Education Program Adult Treatment Panel (modified ATP III) and International Diabetes Federation (IDF). Methods This cross-sectional study included 5,584 adults at age 20-79 randomly selected from Pudong New Area of Shanghai, China, through a three-stage sampling. All participants were interviewed in-person between April and July of 2008 to collect information on demographic and lifestyle characteristics. At the interview, anthropometry and blood pressure were measured and bio-specimens were collected. Results The prevalence estimates for the MS increased with age for each definition in men and women, but the estimates varied greatly between the definitions and by sex. The prevalence of the MS was higher in men (20.2%) than in women (18.7%) using WHO definition but this sex difference was reversed when using the modified ATP III (28.4% for men vs. 35.1% for women) and the IDF (15.9% for men vs. 26.7% for women) criteria. The most common metabolic disorder in this population was dyslipidaemia, regardless of the definition used. Substantial agreement, estimated using the kappa statistic, was found between the modified ATP III and IDF definition, whereas the lowest agreement was observed between the WHO and ATP III criteria. Conclusions The MS is highly prevalent among Chinese adults in Pudong New Area of Shanghai and the most prevalent component was dyslipidemia. These findings underscore the importance of prevention and control efforts for the MS in this area and the need for a unified predictive definition for the syndrome for use by clinical practitioners and public health agencies.
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机译：背景技术近年来，中国的代谢综合征（MS）患病率一直在上升。这项研究的目的是使用世界卫生组织（WHO），国家胆固醇教育计划成人治疗小组（修订版）提出的定义，估计和比较中国最经济发达地区之一上海的中国成年人中MS的患病率。 ATP III）和国际糖尿病联合会（IDF）。方法这项横断面研究通过三阶段抽样，从中国上海市浦东新区随机抽取了5584名20-79岁的成年人。在2008年4月至7月期间，所有参与者都接受了现场采访，以收集有关人口统计和生活方式特征的信息。在访谈中，测量了人体测量学和血压，并收集了生物样本。结果在男性和女性中，每种定义的MS患病率估计值都随着年龄的增长而增加，但是在定义之间和性别之间的估计值差异很大。根据WHO定义，男性的MS患病率高于男性（20.2％），高于女性（18.7％），但使用改良的ATP III（男性为28.4％，女性为35.1％）和IDF可以逆转这种性别差异。 （男性为15.9％，女性为26.7％）。无论使用何种定义，该人群中最常见的代谢紊乱是血脂异常。在修改后的ATP III和IDF定义之间发现了使用kappa统计量估算的实质一致性，而在WHO和ATP III标准之间发现的一致性最低。结论MS在上海浦东新区的中国成年人中高度流行，最普遍的成分是血脂异常。这些发现强调了在这一领域对MS进行预防和控制工作的重要性，以及需要为临床从业者和公共卫生机构使用该综合征的统一预测定义。
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