LEAK study: design of a nationwide randomised controlled trial to find the best way to treat wound leakage after primary hip and knee arthroplasty

Karin M Vermeulen; Inge van den Akker-Scheek; Frank-Christiaan Wagenaar; Martin Stevens; Marjan Wouthuyzen-Bakker; Rudolf W Poolman; Claudia A M L?wik; Yvette Pronk; Sjoerd K Bulstra; Paul C Jutte; Walter van der Weegen; Rob G H H Nelissen

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LEAK study: design of a nationwide randomised controlled trial to find the best way to treat wound leakage after primary hip and knee arthroplasty

机译：泄漏研究：一项全国性随机对照试验的设计，以寻找治疗原发性髋关节和膝关节置换术后伤口渗漏的最佳方法

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Abstract Introduction Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are highly successful treatment modalities for advanced osteoarthritis. However, prolonged wound leakage after arthroplasty is linked to prosthetic joint infection (PJI),

机译：摘要简介全髋关节置换术（THA）和全膝关节置换术（TKA）是晚期骨关节炎的高度成功的治疗方法。但是，关节置换术后伤口渗漏时间延长与人工关节感染（PJI）有关，

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《BMJ Open》 |2017年第12期|共页
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Karin M Vermeulen; Inge van den Akker-Scheek; Frank-Christiaan Wagenaar; Martin Stevens; Marjan Wouthuyzen-Bakker; Rudolf W Poolman; Claudia A M L?wik; Yvette Pronk; Sjoerd K Bulstra; Paul C Jutte; Walter van der Weegen; Rob G H H Nelissen;
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中图分类临床医学;
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1. Assessment of the effect of addition of 24 hours of oral tranexamic acid post-operatively to a single intraoperative intravenous dose of tranexamic acid on calculated blood loss following primary hip and knee arthroplasty (TRAC-24): a study protocol for a randomised controlled trial [J] . Janet Hill, Paul Magill, Alastair Dorman, Trials . 2018,第1期

机译：在初级髋关节和膝关节成形术（TRAC-24）之后，对单一术中静脉内剂量的单一脑内静脉剂量的宁intr静脉酸性术后进行24小时口服促ranexamic酸的效果（TRAC-24）：随机对照试验的研究方案
2. Open-label randomized controlled trial to compare wound dressings for patients undergoing hip and knee arthroplasty: study protocol for a randomized controlled trial [J] . Maria López-Parra, Dolors Gil-Rey, Esmeralda López-González, Trials . 2018,第1期

机译：开放标签随机对照试验，用于比较髋关节和膝关节置换术患者的伤口敷料：随机对照试验的研究方案
3. Combined use of intravenous and topical versus intravenous tranexamic acid in primary total knee and hip arthroplasty: a meta-analysis of randomised controlled trials [J] . Jun-feng Li, Hang Li, Hui Zhao, Journal of Orthopaedic Surgery Research . 2017,第1期

机译：静脉和局部静脉注射氨甲环酸联合静脉使用氨甲环酸在原发性全膝和髋关节置换术中的应用：一项随机对照试验的荟萃分析
4. Implant alignment and quality of life following computer-assisted total knee arthroplasty: a prospective comparative randomised multicenter study [C] . Louis Roy, Francois Poulin, Louis-Philippe Amiot International Society for Computer Assisted Orthopaedic Surgery. Meeting . 2007

机译：计算机辅助全膝关节置换术后植入对准和生活质量：一项前瞻性随机化多中心研究
5. Relationships between pre-operative education, patient self-efficacy, patient anxiety, body mass index, and patient satisfaction of geriatric patients receiving primary total hip or total knee arthroplasty. [D] . Macchiaroli, Julia M. 2012

机译：接受全髋或全膝置换的老年患者的术前教育，患者自我效能，患者焦虑，体重指数和患者满意度之间的关系。
6. LEAK study: design of a nationwide randomised controlled trial to find the best way to treat wound leakage after primary hip and knee arthroplasty [O] . Claudia A M Löwik, Frank-Christiaan Wagenaar, Walter van der Weegen, 2017

机译：泄漏研究：一项全国性随机对照试验的设计以寻找治疗原发性髋关节和膝关节置换术后伤口渗漏的最佳方法
7. Open-label randomized controlled trial to compare wound dressings for patients undergoing hip and knee arthroplasty: study protocol for a randomized controlled trial [O] . Maria López-Parra, Dolors Gil-Rey, Esmeralda López-González, 2018

机译：开放标签随机对照试验，用于比较髋关节和膝关节置换术患者的伤口敷料：随机对照试验的研究方案

LEAK study: design of a nationwide randomised controlled trial to find the best way to treat wound leakage after primary hip and knee arthroplasty

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