The application of thromboelastogram in detection of indexes of antiplatelet therapy for coronary heart disease

摘要

Background: This study aims to explore the application value of thromboelastogram (TEG) in antiplatelet therapy in coronary artery intervention. Methods: A retrospective analysis of 90 cases of coronary interventional treatment was conducted in our hospital from January 2010 to January 2012. Cases were divided into three groups, according to the kind of coronary heart disease: angina pectoris (AP) group (30 cases), unstable angina pectoris (UAP) group (30 cases) and acute myocardial infarction (AMI) group (30 cases). TEG changes in patients between the three groups were analyzed. Results: The differences in international normalized ratio (INR) and activated partial thromboplastin time (APTT) indexes among the three groups of patients were statistically significant (P 2 =4.261, 3.908; P 2 =5.026; P Conclusions: The detection of indexes of antiplatelet therapy in coronary artery intervention is helpful for antiplatelet medication, thus can effectively reduce the incidence of ischemic events.