VALIDATION OF A LIQUID CHROMATOGRAPHY-FLUORESCENCE SPECTROMETRIC METHOD FOR THE QUANTIFICATION OF FOUR QUINOLONES IN PIG AND CHICKEN MUSCLE FOLLOWING THE EUROPEAN UNION GUIDELINE EC/657/2002

摘要

Quinolones are a group of structurally related antibacterial compounds. Over the last years their use in animal production has been greatly increased. This increase can cause the resistance of bacteria. In order to protect human health the European Union (EU), as well as other countries, has established Maximum Residue Limits (MRL) for these antibacterial agents in several foods. Among these foods, pig and chicken muscle have different MRLs in the sub-ppm range.