SIMULTANEOUS DETERMINATION OF PIPERACILLIN AND TAZOBACTAM IN THE PHARMACEUTICAL FORMULATION TAZONAM? BY DERIVATIVE SPECTROPHOTOMETRY

摘要

In this paper, a simple and rapid method was developed for the simultaneous determination of Piperacillin (PIP) and Tazobactam (TAZ) by second-order derivative spectrophotometry. Water was selected as a solvent for extraction and determination of both analytes. Further studies of photo-stability and forced degradation for both drugs were also performed.