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CMV co‐infection and risk of AIDS and non‐AIDS events in a large cohort of HIV‐infected patients

机译:在一大批受HIV感染的患者中,CMV合并感染以及AIDS和非AIDS事件的风险

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In HIV‐positive patients (pts), CMV co‐infection has been proposed as a key factor in sustaining immune activation, which in turn could play a role in determining immune senescence. We evaluated the prevalence and predictors of CMV co‐infection in a cohort of HIV+ pts and assessed the impact of CMV co‐infection on the risk of AIDS and non‐AIDS events. We included pts in the ICONA study with10 cp/mL higher 1.05 0.96–1.16 0.26 Years from HIV diagnosis per 5 years longer 1.02 0.90–1.17 0.69 ART experienced vs. na?ve at baseline 0.94 0.66–1.36 0.77
机译:在HIV阳性患者(pts)中,CMV共感染被认为是维持免疫激活的关键因素,而后者又可能在确定免疫衰老中发挥作用。我们评估了一组HIV +人群中CMV合并感染的患病率和预测因素,并评估了CMV合并感染对艾滋病和非艾滋病风险的影响。在ICONA研究中,我们将pts升高了10 cp / mL 1.05 0.96-1.16 0.26每5年从HIV诊断开始的时间延长了1.02 0.90-1.17 0.69经历过ART相对于朴素的0.94 0.66-1.36 0.77

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