Rituximab in Steroid-Resistant Nephrotic Syndrome in Children: A (False) Glimmer of Hope?

摘要

Idiopathic nephrotic syndrome in childhood is responsive to treatment with steroids in the majority of cases. Its main causes are minimal change nephropathy (MCNS) and focal segmental glomerulosclerosis (FSGS). Approximately 10%–15% of children with idiopathic nephrotic syndrome are steroid.