Is the Kidney Always the Cause of Hypertension? Distinct Roles for the Kidney and Systemic Tissues in Blood Pressure Regulation by the Renin-Angiotensin System. J Clin Invest 115: 1092a€“1099, 2005

摘要

In the past wise rabbis had stated: a€?The human body was given ten organs of which it is the task of the kidney to provide the human body with thoughta€? (Talmud Brochot). This view of the kidney, although immensely flattering to nephrologists, is no longer universally accepted today. A remaining source of pride in nephrology, however, was the conviction that the kidney was the central, if not unique, player in the genesis of all forms of hypertension.