A simple synthesis of the regiospecifically deuterium-labeled herbicide MCPA-isopropyl

摘要

In order to investigate the metabolism of the herbicide MCPA-isopropyl [isopropyl 2-(4-chloro-2-methylphenoxy)acetate] in the environment, two isotopologues of this regiospecifically deuterium-labeled in selected positions compound were synthesized. The synthesized compounds were labeled at the methylene group, isopropyl 2-(4-chloro-2-methylphenoxy)[2,2-2H₂]acetate, and at the isopropyl group, [2H₇]isopropyl 2-(4-chloro-2-methylphenoxy)acetate.