Association between dental caries indicators and serum glycated hemoglobin-levels among patients with type 2 diabetes mellitus

摘要

Diabetes mellitus (DM) with poor glycemiccontrol is often linked to oral manifestations. Thisstudy aimed to investigate the association betweendental caries (DC) and glycated hemoglobin (HbA1c)among patients with type 2 DM (T2DM). A healthcenter-based cross-sectional study was conductedcomprising 91 eligible patients with T2DM (21 malesand 70 females) with a mean age (± standard deviation)of 61.49 ± 9.71 years. A structured interview,screening for DM-related factors, and oral examinationwere performed. Serum HbA1c levels wereused as an index for glycemic control. A comparisonbetween patients with controlled T2DM, i.e., HbA1c≤7.0% (n = 46), and uncontrolled T2DM, i.e., HbA1c7.0% (n = 45), showed significant differences in meanvalues of decayed teeth (DT) (P = 0.045); missing teeth(P = 0.002); and decayed, missing, and filled teeth(DMFT) index (P 0.001). Results of multiple linearregression analysis revealed that the number of DTwas significantly correlated with serum HbA1c levels(95% confidence interval [CI] 0.173 to 0.972, P =0.005). Furthermore, DMFT index values and serumHbA1c levels (95% CI 0.532 to 1.658, P 0.001)showed a significant association. This study providessubstantial evidence on the association between DCindicators and serum HbA1c levels.