A Pharmacokinetic Study to Compare Two Simultaneous 400 μg Doses with a Single 800 μg Dose of Oral Transmucosal Fentanyl Citrate

摘要

It is unknown whether two smaller doses of oral transmucosal fentanyl citrate (OTFC) administered simultaneously are pharmacokinetically equivalent to an identical dose administered as a single unit. This issue has important practical implications when pa