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Degree, duration, and causes of visual impairment in eyes affected with ocular tuberculosis

机译:眼结核病患者的眼睛的程度,持续时间和视力障碍的原因

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Ocular tuberculosis (TB) can affect nearly every ocular tissue, leading to a variety of vision-threatening clinical manifestations. The goal of this study is to estimate the degree, duration, and causes of visual impairment in eyes affected by ocular TB. This was a retrospective study of patients diagnosed as ocular TB based on polymerase chain reaction (PCR) for Mycobacterium tuberculosis complex. We applied the World Health Organization definition of visual impairment (VI) to affected eye(s), instead of better-seeing eye. Best-corrected visual acuity (BCVA) of <6/18 and ≥6/60 in the affected eye was classified as moderate VI and <6/60 and ≥3/60 as severe VI. Data collected included presenting and final BCVA of affected eyes and the worst BCVA during the study period. Sixty-one eyes of 40 patients were analyzed. Twenty-five patients (52.1%) had bilateral disease. The mean worst BCVA and mean final BCVA (logMAR) were 1.26?±?0.87 and 0.61?±?0.85, respectively, and their difference was highly significant (p?
机译:眼结核(TB)几乎可以影响每个眼组织,从而导致多种威胁视力的临床表现。这项研究的目的是估计受眼结核病影响的眼睛的程度,持续时间和视觉障碍的原因。这是一项基于聚合酶链反应(PCR)诊断为结核分枝杆菌复合体的眼结核患者的回顾性研究。我们将世界卫生组织对视力障碍(VI)的定义应用于受影响的眼睛,而不是视力更好的眼睛。患眼的最佳矫正视力(BCVA)<6/18和≥6/ 60被分类为中度VI,<6/60和≥3/ 60被分类为重度VI。收集的数据包括研究期间患眼的呈现和最终BCVA,以及研究期间最严重的BCVA。分析了40例患者的61只眼。二十五例患者(52.1%)患有双侧疾病。平均最差BCVA和平均最终BCVA(logMAR)分别为1.26±±0.87和0.61±±0.85,它们之间的差异非常显着(p?<0.0001,Friedman检验)。中位数最差和最终BCVA结果分别为1.30(范围为0.0到3.0)和0.20(范围为0.0到3.0)。平均随访时间为98.34±81.81周。在随访过程中,分别在14只眼(22.9%)和12只眼(19.7%)中观察到了中度和重度VI。二十只眼(32.8%)的BCVA <3/60。中度VI或更严重的情况最常见于患有多灶性蛛网膜脉络膜脉络膜炎(n?=?6; 100%),视网膜血管炎(n?=?25; 80.6%)和胰腺炎(n?=?12; 80%)的眼中。视力丧失的平均持续时间为25.2±±42.37周(中位数为6.43周,范围为0至206.42周)。玻璃体出血,复杂性白内障和黄斑瘢痕是VI的常见原因。眼结核可导致长时间的视力障碍,更常见于后葡萄膜炎或胰腺炎。

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