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首页> 外文期刊>Journal of neurological sciences (Turkish) >Spinal Leptomeningeal Metastasis Of Cerebral Glioblastoma Multiforme In A Child
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Spinal Leptomeningeal Metastasis Of Cerebral Glioblastoma Multiforme In A Child

机译:小儿多发性脑胶质母细胞瘤的脊髓软脑膜转移

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The spreading of cerebral glioblastoma multiforme into the spinal canal and causing clinical symptoms are seen rarely. An 11-year-old male patient was admitted to our clinic with headache. Cerebral MRI showed a contrast enhanced lesion in the occipital horn of the lateral ventricle which was approximately 3x4x3 cm in diameter. The tumour was totally resected. Pathological diagnosis of the tumour revealed glioblastoma multiforme. On control MRI there was not residual tumour. Cranial radiotherapy and chemotheraphy was applied. Five months later, he was admitted again to our clinic because of sudden onset of severe lumbago, and disability of walking. Spinal MRI demonstrated multifocal spread of glioblastoma multiforme, including intradural intramedullar spinal drop metastases at the level of cervico-thoracic vertebrae (between C7 and T10) and intradural lumbosacral region. Radiotherapy and chemotheraphy was not applied again. The patient with a mean follow up period of 5 months was uneventful, and he has been paraparesis for 6 months.
机译:很少见到多形性脑胶质母细胞瘤扩散到椎管内并引起临床症状。一名11岁的男性患者因头痛入院。脑MRI显示侧脑室枕角处的造影剂病变增强,直径约3x4x3 cm。肿瘤被完全切除。肿瘤的病理诊断显示多形性胶质母细胞瘤。在对照MRI上,没有残留肿瘤。应用颅放射疗法和化学疗法。五个月后,他因严重腰痛突然发作且无法行走而再次入院。脊柱MRI显示多形性胶质母细胞瘤的多灶性扩散,包括在颈胸椎椎骨(C7和T10之间)和硬膜内腰s部区域的硬膜内髓内脊髓内转移。放疗和化学疗法不再适用。平均随访期为5个月的患者平安无事,他已经进行了截瘫6个月。

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