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首页> 外文期刊>Journal of Microbial & Biochemical Technology >Effective Antimicrobial Coatings Containing Silver-Based Nanoclays and Zinc Pyrithione
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Effective Antimicrobial Coatings Containing Silver-Based Nanoclays and Zinc Pyrithione

机译:含银基纳米粘土和吡啶并酮锌的有效抗菌涂层

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Increased antibiotic resistance in human pathogens leads to the development of new preventive measures. The introduction of antimicrobial materials and surfaces provides an alternative tool for controlling harmful microorganisms. This article is focused on a study regarding the potential role of two new antimicrobial surface coatings in the control of infection spread. The method applied was to compare the antimicrobial activity of BactiBlock?-treated coatings respect to untreated coatings, which were used as control, following international standards. The antibacterial activity of two antimicrobial polymer-based coatings containing silver-based antimicrobial layered silicate additive (BactiBlock? 635 A1 and BactiBlock? 655 A0) was tested according to JIS Z 2801 against S. aureus, MRSA, VRE, K. pneumoniae, P. aeruginosa, A. baumannii and E. coli. BactiBlock? 635 A1 also contains 0.25% of zinc pyrithione (ZnP). The antifungal activity was tested according to ISO 846 against A. niger. The two coatings presented a strong antibacterial broad-spectrum activity (R ≥ 2, p<0.01). The coating with ZnP also showed a strong antifungal activity, since no fungi growth was detected on the treated surface after 4 weeks. Nevertheless, these findings support the potential of these polymer-based coatings as a tool that would help to prevent the colonization of inert surfaces by harmful microorganisms and protect patients and consumers who are exposed daily.
机译:人类病原体中抗生素耐药性的提高导致新的预防措施的发展。抗菌材料和表面的引入为控制有害微生物提供了另一种工具。本文专注于有关两种新型抗菌表面涂层在控制感染扩散中的潜在作用的研究。所采用的方法是按照国际标准比较经BactiBlock?处理过的涂料相对于未经处理的涂料(作为对照)的抗菌活性。根据JIS Z 2801,测试了两种含银基抗菌层状硅酸盐添加剂(BactiBlock?635 A1和BactiBlock?655 A0)的抗菌聚合物基涂料对金黄色葡萄球菌,MRSA,VRE,肺炎克雷伯菌,P的抗菌活性。铜绿假单胞菌,鲍曼不动杆菌和大肠杆菌。 BactiBlock? 635 A1还包含0.25%的巯氧吡啶锌(ZnP)。根据ISO 846针对黑曲霉测试抗真菌活性。两种涂层均具有很强的抗菌广谱活性(R≥2,p <0.01)。 ZnP涂层还显示出很强的抗真菌活性,因为4周后在处理过的表面上未检测到真菌生长。然而,这些发现支持了这些基于聚合物的涂料作为工具的潜力,该工具将有助于防止有害微生物在惰性表面上定殖并保护每天接触的患者和消费者。

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