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首页> 外文期刊>Journal of Krishna Institute of Medical Sciences University. >Control of Intraoperative Shivering Under Spinal Anaesthesia- A Prospective Randomized Comparative Study of Butorphanol with Tramadol
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Control of Intraoperative Shivering Under Spinal Anaesthesia- A Prospective Randomized Comparative Study of Butorphanol with Tramadol

机译:脊髓麻醉下术中颤抖的控制-布托啡诺与曲马多的前瞻性随机比较研究

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Background: distressing for the patient, anaesthesiologist and the surgeon, especially when the patient is under regional anaesthesia. Aim and Objectives: was designed to evaluate the efficacy of butorphanol and tramadol in the control of shivering under spinal anaesthesia and to compare their side effects. To compare the efficacy, potency, response time, hemodynamic alterations, and adverse effects of intravenously administered tramadol and butorphanol for relief of shivering occurring during spinal anaesthesia. Material and Methods: This randomised prospective study was conducted in 100 patients who developed shivering under spinal anaesthesia during various abdominal, orthopaedic, urological and gynaecological procedures. Patients with fever, acute infections, drug allergy and compromised cardiorespiratory functions were not included in the study. On shivering, patients were randomly allocated in two groups of 50 patients each who received intravenously 1mg of butorphanol or 50 mg of tramadol in a double blinded manner. Control of shivering, time taken for cessation, recurrence, hemodynamic changes, axillary temperatures and side effects were noted and compared for both the groups. Collected data were analysed using Chi square test and Student's unpaired t test. Results: All patients were relieved of shivering after butorphanol, 58% within 1 min, 82% within 3min and 100% within 5 min. Tramadol relieved shivering in 98% of patients, 32% within 1 min, 60% within 3 min, 98% within 5 mins (p 0.05). There was higher incidence of side effects like nausea and vomiting with tramadol (16% and 12% respectively) as compared to butorphanol. Conclusion: Both the drugs, tramadol and butorphanol are effective to control shivering after spinal anaesthesia. Butorphanol is better as compared to tramadol in treating shivering under spinal anaesthesia because of its quicker onset of action, higher success rate and fewer side effects like nausea and vomiting.
机译:背景:给患者,麻醉师和外科医生带来困扰,尤其是当患者处于局部麻醉状态时。目的和目的:旨在评估布托啡诺和曲马多在脊髓麻醉下控制发抖的功效,并比较它们的副作用。为了比较在麻醉过程中静脉注射曲马多和布托啡诺用于缓解抽搐的疗效,效力,反应时间,血液动力学改变和不良反应。材料和方法:这项随机前瞻性研究针对100名在各种腹部,骨科,泌尿科和妇科手术过程中在脊髓麻醉下发抖的患者进行。发热,急性感染,药物过敏和心肺功能受损的患者未纳入研究。瑟瑟发抖时,将患者随机分为两组,每组50名,分别以双盲方式静脉注射1mg的布托啡诺或50mg的曲马多。记录了两组的颤抖控制,戒断时间,复发,血液动力学变化,腋窝温度和副作用,并进行了比较。使用卡方检验和学生不成对t检验分析收集的数据。结果:所有患者在使用丁苯啡诺后均缓解了寒战,1分钟内58%,3分钟内82%,5分钟内100%。曲马多缓解了98%的患者的颤抖,在1分钟内缓解了32%,在3分钟内缓解了60%,在5分钟内缓解了98%(p <0.05)。曲马多的不良反应如恶心和呕吐的发生率比丁烷醇更高(分别为16%和12%)。结论:曲马多和布托啡诺两种药物均能有效控制脊髓麻醉后的发抖。相比于曲马多,布托啡诺在脊髓麻醉下治疗发抖的效果优于曲马多,因为它起效更快,成功率更高,并且恶心和呕吐等副作用更少。

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