High Stimulation Index for Quail Egg Yolk After an Allergen-Specific Lymphocyte Stimulation Test in a Child With Quail Egg–Induced Food Protein– Induced Enterocolitis Syndrome

摘要

Eggs are one of the most common causes of IgE-mediated food allergy in children worldwide. In a retrospective cohort study in the US, chicken egg was the fifth most commonly involved allergen in food protein–induced enterocolitis syndrome (FPIES) and was responsible for 11% of cases [1]. A patient with IgE-mediated chicken egg allergy usually avoids other types of bird egg owing to cross-reactivity between IgE antibodies and allergens [2]. However, the major antigens and cross-reactivity in bird egg–induced FPIES are not fully understood, and there are few reports of FPIES induced by quail egg in children who had no symptoms after ingesting chicken egg [3,4]. We report the results of a double blind, placebo-controlled food challenge (DBPCFC) and allergic in vitro testing in a 7-year-old Japanese girl with FPIES to quail egg but not to chicken egg.