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Urticarial Vasculitis in a Teenage Girl

机译:一名少女的荨麻疹性血管炎

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This case involves a 13-year-old female who presented to the pediatrician for a routine check-up with complaints of a long history of intermittent diarrhea followed by a severe rash lasting for up to a week afterwards. The mother had described her daughter’s condition to multiple physicians, several whom had seen her during flare-ups. The nonmigratory lesions resembled “hives” with a single lesion lasting for 48 to 72 hours and resolving into what her parent described as a bruise. They often diagnosed her daughter with urticaria and prescribed steroids, which did resolve the acute flare-ups. None of the physicians, however, focused on the disease’s evolution and chronicity in an effort toward diagnosis and prevention. The patient was referred by her pediatrician to a dermatologist who diagnosed the patient with urticarial vasculitis. She was initially started on dapsone 25 mg and was increased over a period of months to a maintenance dose of 100 mg daily. She has had no recurrences in her cutaneous or systemic symptoms on this dose. She is closely monitored by her dermatologist on a regular basis with twice yearly complete blood counts. Several attempts have been made to discontinue the dapsone, resulting in a flare of her gastrointestinal symptoms. This patient suffered with this condition for almost 10 years. This is a reminder that spending extra time to think through a patient’s problem early on may prevent years of suffering for patients and their families.
机译:该病例涉及一名13岁的女性,该女性就诊于儿科医生进行例行检查,并抱怨其间断性腹泻病史悠久,随后出现了长达一周的严重皮疹。这位母亲向多位医生描述了女儿的病情,几位医生在突然发作时见过她。非迁移性病变类似于“荨麻疹”,单个病变持续48到72小时,并解决了她父母所说的瘀伤。他们经常诊断出女儿患有荨麻疹和处方的类固醇激素,这确实解决了急性发作。但是,没有一个医生专注于疾病的演变和慢性病,以进行诊断和预防。儿科医生将患者转诊给诊断为荨麻疹性血管炎的皮肤科医生。她最初以25毫克氨苯砜开始服用,并在数月内逐渐增加至每天100毫克的维持剂量。在此剂量下,她的皮肤或全身症状没有复发。皮肤科医生定期对她进行定期监测,每年两次进行全血细胞计数。已经进行了几次尝试来中止氨苯砜,导致其胃肠道症状发作。该患者患有此病近10年。这提醒我们,花额外的时间尽早思考患者的问题可能会避免患者及其家人遭受数年的痛苦。

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