Prevalence of vitamin D deficiency in critically ill patients and its influence on outcome: experience from a tertiary care centre in North India (an observational study)

摘要

BackgroundLimited studies are available on prevalence and severity of vitamin D deficiency in a critically ill population. To the best of our knowledge, this the first study of its kind in an Indian intensive care set-up. MethodsOne hundred fifty-eight critically ill patients were prospectively enrolled for over 2?years. Demographic profile and clinical characteristics were noted. Blood sample for serum 25 (OH) D was collected on admission (4?ml). Serum 25 (OH) D was measured using radioimmunoassay kit. Vitamin D deficiency was labelled as insufficient (31–60?nmol/l), deficient (15–30?nmol/l) and undetectable ( ResultsVitamin D deficiency ( ConclusionsVitamin D deficiency is highly prevalent in critically ill patients. A causal association between vitamin D deficiency and mortality was not found in our study. Larger studies are needed to understand the relationship between vitamin D deficiency and ICU outcome.